Email this article Fourth-order derivative spectrophotometric method for simultaneous determination of pseudoephedrine and naproxen in pharmaceutical dosage forms
Abstract
Combination dosage forms of naproxen sodium and pseudoephedrine hydrochloride are used for symptomatic treatment of cold and sinus disorders. In this study, fourth-order derivative spectrophotometric method was used for simultaneous determination of naproxen sodium and pseudoephedrine hydrochloride. The method was linear over the range of 2-28 μg/ml for pseudoephedrine hydrochloride and 4-200 μg/ml for naproxen sodium. The within-day and between-day coefficient of variation values were less than 5.8% and 2.5% for pseudoephedrine hydrochloride and naproxen sodium, respectively. The application of the proposed method for simultaneous determination of naproxen and pseudoephedrine in dosage forms was demonstrated without any special pretreatment.
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Brunton L, Parler K, Blumenthal D, Buxton I. Goodman and Gillman's Manual of Pharmacology and Therapeutics. New York: McGraw-Hill medical publishing division; 2008. p. 166, 452.
Karakus S, Kucukguzel I, Kucukguzel SG. Development and validation of a rapid RP-HPLC method for the determination of cetirizine or fexofenadine with pseudoephedrine in binary pharmaceutical dosage forms. J Pharm Biomed Anal. 2008;46:295-302.
Hadad GM, Emara S, Mahmoud WM. Development and validation of a stability- indicating RP-HPLC method for the determination of paracetamol with dantrolene or/and cetirizine and pseudoephedrine in two pharmaceutical dosage forms. Talanta. 2009;79:1360-1397.
Likar MD, Mansour HL, Harwood JW. Development and validation of a dissolution test for a once-a-day combination tablet of immediate-release cetirizine dihydrochloride and extended-release pseudoephedrine hydrochloride. J Pharm Biomed Anal. 2005;39:543-551.
Manassra A, Khamis M, el-Dakiky M, Abdel-Qader Z, Al-Rimawi F. Simultaneous HPLC analysis of pseudoephedrine hydrochloride, codeine phosphate, and triprolidine hydrochloride in liquid dosage forms. J Pharm Biomed Anal. 2010;51:991-993.
Kalogria E, Koupparis M, Panderi I. A porous graphitized carbon column HPLC method for the quantification of paracetamol, pseudoephedrine, and chlorpheniramine in a pharmaceutical formulation. J AOAC Int. 2010;93:1093-1101.
Haggag RS, Belal TS. Gradient HPLC-DAD determination of two pharmaceutical mixtures containing the antihistamine drug ebastine. J Chromatogr Sci. 2012;50:862-868.
Makino Y. Simple HPLC method for detection of trace ephedrine and pseudoephedrine in ligh- purity methamphetamine. Biomed Chromatogr. 2012;26:327-330.
Caglar S, Toker SE. Simultaneous determination of desloratadine and pseudoephedrine sulfate in tablets by high performance liquid chromatography and derivative spectrophotometry. Rev Anal Chem. 2011;30:145-151.
Altuntas TG, Zanooz SS, Nebioglu D. Quantitative determination of acrivastine and pseudoephedrine hydrochloride in pharmaceutical formulation by high performance liquid chromatography and derivative spectrophotometry. J Pharm Biomed Anal. 1998;17:103-109.
Mobrouk MM, El-Fatatry HM, Hammad S, Wahbi AAM. Simultaneous determination of loratadine and pseudoephedrine sulfate in pharmaceutical formulation by RP-LC and derivative spectrophotometry. J Pharm Biomed Anal. 2003;33:597-604.
Monser L, Darghouth F. Simultaneous determination of naproxen and related compounds by HPLC using porous graphitic carbon column. J Pharm Biomed Anal. 2003;32:1087-1092.
Venkatarao P, Nagendra Kumar M, Ravi Kumar M. Novel validated stability-indicating UPLC method for the estimation of naproxen and its impurities in bulk drugs and pharmaceutical dosage form. Sci Pharm. 2012;80:965-976.
Rao KT, Rao LV. A validated stability-indicating UHPLC method for determination of naproxen and its related compounds in bulk drug samples. Am J Anal Chem. 2013;4:286-292.
Hsu YH, Liou YB, Lee JA, Chem CY, Wu AB. Assay of naproxen by high-performance liquid chromatography and identification of its photoproducts by LC-ESI MS. Biomed Chromatogr. 2006;20:787-793.
Wahbi AA, Mabroul MM, Moneeb MS, Kamal AH. Simultaneous determination of the two non-steroidal anti-inflammatory drugs, diflunisal and naproxen in their tablets by chemometric spectrophotometry and HPLC. Pak J Pharm Sci. 2009;22:8-17.
Reddy YR, Kumar KK, Reddy MRP, Mukkanti K. Rapid simultaneous determination of sumatriptan succinate and naproxen sodium in combined tablets by validated ultra performance liquid chromatographic method. J Anal Bioanal Tech. 2011;2:121.
Jain DK, Jain N, Charde R, Jain N. The RP-HPLC method for simultaneous estimation of esomeprazole and naproxen in binary combinations. Pharm Methods. 2011;2:167-172.
Murtha JL, Julian TN, Radebaugh GW. Simultaneous determination of pseudoephedrine hydrochloride, chlorpheniramine maleate and dextromethorphan hydrobromide by second-derivative photodiode array spectroscopy. J Pharm Sci. 1988;77:715-718.
Ivanovic D, Medenica M, Markovic S, Mandic G. Second-derivative spectrophotometric assay of pseudoephedrine, ibuprofen and loratadine in pharmaceuticals. Arzneimittelforschang. 2000; 50:1004-1008.
Onur F, Yucesoy C, Dermis S, Kartal M, kakdil G. Simultaneous determination of pseudoephedrine sulfate, dexbromopheniramine maleate and loratadine in pharmaceutical preparations using derivative spectrophotometry and ratio spectra derivative spectrophotometry. Talanta. 2000;51:269-279.
Mahgoub H, Gazy AA, El-Yazbi FA, El-Sayed MA, Youssef RM. Spectrophotometric determination of binary mixtures of pseudoephedrine with some histamine H1-receptor antagonists using derivative ratio spectrum method. J Pharm Biomed Anal. 2003;31:801-809.
Palabiyik IM, Dinc E, Onur F. Simultaneous spectrophotometric determination of pseudoephedrine hydrochloride and ibuprofen in a pharmaceutical preparation using ratio spectra derivative spectrophotometry and multivariate calibration techniques. J Pharm Biomed Anal. 2004;34:473-483.
Maggio RM, Castellano PM, Vignaduzzo SE, Kaufman TS. Alternative and improved method for the simultaneous determination of fexofenadine and pseudoephedrine in their combined tablet formulation. J Pharm Biomed Anal. 2007;45: 804-810.
Riahi S, Hadiloo F, Milani SM, Davarkhah N, Ganjali MR, Norouzi P, et al. A new technique for spectrophotometric determination of pseudoephedrine and guaifenesin in syrup and synthetic mixture. Drug Test Anal. 2011;3:319-324.
El-Kommos ME, Mohamed NA, Hakiem AF. Extractive spectrophotometric determination of some nonsteroidal anti-inflammatory drugs using methylene blue. J AOAC Int. 2013;96:737-744.
Damiani P, Bearzotti M, Cabezon MA. Spectrofluorometric determination of naproxen in tablets. J Pharm Biomed Anal. 2002;29:229-238.
Ekpe A, Tong JH, Rodriguez L. High-performance liquid chromatographic method development and validation for the simultaneous quantitation of naproxen sodium and pseudoephedrine hydro-chloride impurities. J Chromatogr Sci. 2001;39: 81-86.
Dinc E, Ozdemir A, Aksoy H, Ustundag O, Baleanu D. Chemometric determination of naproxen sodium and pseudoephedrine hydrochloride in tablets by HPLC. Chem Pharm Bull (Tokyo). 2006;54: 415-421.
Souri E, Jalalizadeh H, Farsam H, Ghadiri R, Amanlou M. Simultaneous determination of cyproterone acetate and ethinyl estradiol in tablets by derivative spectrophotometry. Chem Pharm Bull. 2005;53:949-951.
Souri E, Jalalizadeh H, Farsam H, Rezwani H, Amanlou M. Simultaneous determination of anthocyanoside and beta-carotene by third-derivative ultraviolet spectrophotometry. DARU. 2005;13:11-16.
KhuhawarNY, Rind FMA, Rajper A. Determiantion of phenylpropanolamine in pharmaceutical preparations by second derivative spectrophotometry. J Food Drug Anal. 2005;13:388-391.
Souri E, Amanlou M, Farsam H, Afshari A. A rapid derivative spectrophotometric method for simultaneous determination of naphazoline and antazoline in eye drops. Chem Pharm Bull (Tokyo). 2006;54:119-122.
Barazandeh Tehrani M, Namadchian M, Fadaye Vatan S, Souri E. Derivative spectrophotometric method for simultaneous determination of clindamycin phosphate and tretinoin in pharmaceutical dosage forms. DARU. 2013;21:39.
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